Literatur-Liste

In diesem Abschnitt finden Sie einige ausgewählte Publikationen zum Thema Omega-3-Fettsäuren. Wir werden die Liste stetig ergänzen.

Literatur zu Omega-3-Fettsäuren: Stoffwechsel, Wirkungen und allgemeine Gesichtspunkte

  • Singer P., Wirth M., Singer K. (2016): Canned seawater fish with declared content of omega – 3 fatty acids: a novel benefit for dietary practice and research. Eur J Clin Nutr  70: 1093-1094
  • Weylandt  KH. (2016): Docosapentaenoic acid derived metabolites and mediators – The new world of lipid mediator medicine in a nutshell. Eur  J Pharmacol 785: 108 – 115
  • Cicero AFG., Rosticci M., Morbini M., Cagnati M., Grandl E., Parini A., Borghi C. (2016): Lipid – lowering and anti – inflammatory effects of omega 3 ethyl esters and krill oil: a randomized, cross- over , clinical trial. Arch Med Sci 12: 507 – 512
  • Barden AE., Mas E., Mori TA. (2016): n – 3 fatty acid supplementation and proresolving  mediators of inflammation. Curr Opin Lipidol 27: 26 – 32
  • Polus A., Zapala B., Razny U., Gielicz A., Kiec – Wilk B., Malczewska – Malec M., Sanak M., Childs CE., Calder PC., Dembinska – Kiec A. (2016): Omega – 3 fatty acid supplementation influences the whole blood transcriptome in women with obesity , associated with pro – resolving lipid mediator production. Biochim  Biophys  Acta 1861: 1746 – 1755
  • Allaire  J.,Couture  P., Leclerc  M., Charest  A., Marin J., Lepine  M – C., Talbot D., Tchernof  A., Lamarche B. (2016): A randomized, crossover, head – to – head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (Compar ED) study. Am J Clin Nutr 104: 280 – 287
  • Raatz SK., Johnson LK., Rosenberger TA., Picklo MJ. (2016): Twice weekly intake of farmed Atlantic salmon ( Salmo salar) positively influences lipoprotein concentration and particle size in overweight men and women. Nutr Res 36: 899 – 906
  • Moro K., Nagahashi., Ramanathan R., Takabe K., Wakai T. (2016): Resolvins  and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases  and cancer. World J Clin Cases 4: 155 – 164
  • Sorokin  AV., Yang ZH., Vaisman BL., Thacker S., Yu  ZX., Sampson M., Serhan CN., Remaley AT. (2016):  Addition of aspirin to a fish oil – rich diet decreases inflammation and atherosclerosis in ApoE – null mice.     J Nutr Biochim 35: 58 – 65
  • Mozurkewich EL., Greenwood M., Clinton C., Berman D., Romero V., Djuric Z., Qualls C., Gronert K. ( 2016): Pathway markers for pro – resolving lipid mediators in maternal and umbilical cord blood: a secondary analysis of the mothers, omega – 3, and mental health study. Frontiers in Pharmacol 7:1 – 8
  • Stark KD., Van Elswyk ME., Higgins MR., Weatherford CA., Salem N Jr. (2016): Global survey of the omega – 3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults. Prog Lipid Res 63: 132 – 152
  • Hennebelle M., Courchesne – Lover A., St Pierre V., Vandenberghe C., Castellano CA., Fortier M., Tessier D., Cunnane SC. (2016): Preliminary evaluation of a differential effect  of an α – linolenate – rich supplement on ketogenesis and plasma ω – 3 fatty acids in young and older adults. Nutr  32: 1211 – 1216
  • Gellert S., Schuchardt  JP., Hahn A. (2016): Higher omega – 3 index and DHA status in pregnant women compared to lactating woman – results from a German  nation – wide cross – sectional study. Prostaglandins Leucot  Essent  Fatty Acids 109: 22 – 28
  • Dawczynski C., Lorkowski S. (2015): Prävention kardiovaskulärer Erkrankungen. Cardiovasc 15: 38 – 43
  • Bryhn M. (2015): Prevention of sports injuries by marine omega – 3 fatty acids . J Am Coll Nutr 34: 60 – 61
  • Smith GL., Julliand S., Reeds DN., Sinacore DR., Klein S., Mittendorfer B. (2015): Fish oil – derived n – 3 PUFA therapy increases muscle mass and function in healthy older adults. Am J Clin Nutr 102: 115 – 122
  • Lorente – Cebrian S., Costa AG., Navas – Carretero S., Zabala M., Laiglesia LM., Martinez JA., Moreno – Aliaga MJ. (2015):  An update on the role of omega – 3 fatty acids on inflammatory and degenerative diseases. J Physiol Biochem 71: 341 – 349
  • Padro T., Vilahur  G., Sanchez – Hernandez  J., Hernandez  M., Antonijoan  RM., Perez  A., Badimon L. (2015): Lipidomic changes of LDL in overweight and moderately hypercholest subjects taking phytosterol – and omega – 3 – supplemented milk. J Lipid Res 56: 1043 – 1056
  • Ellulu MS., Khaza`ai H., Abed Y., Rahmat A., Ismail P., Ranneh Y. (2015): Role of fish oil in human health and possible mechanism to reduce the inflammation. Inflammopharm 23: 79 – 89
  • Bibus D., Lands B. ( 2015):  Balancing proportions of competing omega – 3 and omega – 6 highly unsaturated fatty acids (HUFA) in tissue lipids. Prostaglandins Leucot  Essent  Fatty Acids 99: 19 – 23
  • Lands B. (2015):  Omega – 3 PUFAs lower the propensity for arachidonic acid cascade overreaction. BioMed Res Int : article ID 285135: 1 – 8
  • Skarke C., Alamuddin N., Lawson JA., Li  X., Ferguson JF., Reilly MP., Fitz Gerald GA. (2015): Bioactive products formed in humans from fish oils. J Lipid Res 56: 1808 – 1820
  • Singer P, Schulz-Berlekamp G, Seyf A (2015): “Eskimodiät” – ein Mythos? Ernährung und Medizin 30: 60 – 68
  • Weylandt KH, Serini S, Chen YQ, Su HM, Lim K,Calviello G (2015): Omega-3 polyunsaturated fatty acids: The way forward in times of mixed evidence. Biomed Res Int: Article ID 143109
  • Fischer S, Glei M (2015): Health aspects of regular consumption of fish and omega-3-fatty acids. Ernahrungs Umschau 62: 140 – 151
  • Zebrowska A, Mizia-Stec K, Mizia M, Gasior Z, Poprzecki S (2015): Omega-3 fatty acids supplementation improves endothelial function and maximal oxygen uptake in endurance – trained athletes. Eur J Sport Sci 15: 305 – 314
  • Lewis EJH, Radonic PW, Wolever TMS, Wells GD (2015): 21 days of mammalian omega-3 fatty acid supplementation improves aspects of neuromuscular function and performance in male athletes compared to olive oil placebo. J Int Soc Sports Nutr 12: 2
  • Fayet-Moore F, Baghurst K, Meyer BJ (2015): Four models including fish, seafood, red meat and enriched foods to achieve Australien Dietary recommendations for n-3 LCPUFA for all life – stages. Nutrients 7: 8602 – 8614
  • Ellulu MS, Khaza’ai H, Abed Y, Rahmat A, Ismail P, Ranneh Y (2015): Role of fish oil in human health and possible mechanism to reduce the inflammation. Inflammopharmacology 23: 79 – 89
  • Miyata J, Arita M (2015): Role of omega 3-fatty acids and their metabolites in asthma and allergic diseases. Allergol Int 64: 27 – 34
  • Skulas-Ray AN, Flock MR, Richter CK, Harris WS, West SG, Kris-Etherton PM (2015): Red blood cell docosapentaenoic acid (DPA n-3) is inversely associated with triglycerides and C-reactive protein (CRP) in healthy adults and dose – dependently increases following n-3 fatty acid supplementation. Nutrients 7: 6390 – 6404
  • Lopez-Vicario C, Alcaraz-Quiles J, Garcia-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BC, Arroyo V, Claria J (2015): Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides. PNAS 112: 536 – 541
  • Elwakeel NM, Hazaa HH (2015): Effect of omega-3 fatty acids plus low – dose aspirin on both clinical and biochemical profiles of patients with chronic peridontitis and type 2 diabetes: a randomized double blind placebo-controlled study. J Peridontal Res 50: 721 – 729
  • von Schacky C, Kemper M, Haslbauer R, Halle M (2014): Low omega-3 index in 106 german elite winter endurance athletes: A pilot study. Int J Sport Nutr Exercise Metab 24: 559 – 564
  • Nagvi AZ, Hasturk H, Mu L, Phillips RS, Davis RB, Halem S, Campos H, Goodson JM, Van Dyke TE, Mukamal KJ (2014): Docosahexaenoic acid and peridontitis in adults: A randomized controlled trial. J Dent Res 93: 767 – 773
  • Molfino A, Gioia G, Fanelli FR, Muscaritoli M (2014): The role for dietary omega-3 fatty acids supplementation in older adults. Nutrients 6: 4058 – 4072
  • Romanatto T, Fiamoncini J, Wang B, Curi R, Kang JX (2014): Elevated tissue omega-3 fatty acid status prevents age – related glucose intolerance in fat-1 transgenic mice. Biochim Biophys Acta 1842: 186 – 191
  • Barden A, Mas E, Croft KD, Phillips M, Mori TA (2014): Short-term n-3 fatty acid supplementation but not aspirin increases plasma proresolving mediators of inflammation. J Lipid Res 55: 2401 – 2407
  • Moosheer SM, Waldschütz W, Itariu BK, Brath H, Stulnig TM (2014): A protein-enriched low glycemic index diet with omega-3 polyunsaturated fatty acid supplementation exerts beneficial effects on metabolic control in type 2 diabetes. Prim Care Diabetes 8: 308 – 314
  • Howe PRC, Buckley JD, Murphy KJ, Pettman T, Milte C, Coates AM (2014): Relationship between erythrocyte omega-3 content and obesity is gender dependent. Nutrients 6: 1850 – 1860
  • Macartney MJ, Hingley L, Brown MA, Peoples GE, McLennan PL (2014): Intrinsic heart rate recovery after dynamic exercise is improved with an increased omega-3 index in healthy males. Br J Nutr 112: 1984 – 1992
  • Papanikolaou Y, Brooks J, Reider C, Fulgoni VL (2014): U.S. adults are not meeting recommended levels for fish and omega-3-fatty acid intake: Results of an analysis using observational data from NHANES 2003 – 2008. Nutr J 13: 31 doi: 10.1186/1475-2891-13-31
  • Schebb NH, Ostermann AL, Yang J, Hammock BD, Hahn A, Schuchardt JP (2014): Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins. Prostaglandins Other Lipid Mediat 113 – 115: 21 – 29
  • Schuchardt JP, Schmidt S, Kressel G, Willenberg I, Hammock BD, Hahn A, Schebb NH (2014): Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men. Prostaglandins Leucot Essent Fatty Acids 90: 27 – 37
  • Lager S, Ramirez V, Gaccioli F, Jansson T, Powell TL (2014): Expression and localization of the omega-3 fatty acid receptor GPR 120 in human term placenta. Placenta 35: 523 – 525 
  • Li J, Li FR, Wei D, Jia W, Kang JX, Stefanovic-Racic M, Dai Y, Zhao AZ (2014): Endogenous ω-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice. Mol Endocrinol 28: 1316 – 1328
  • Singer P, Wirth M, Löhlein I (2014): Fettreiche Seefische in Konserven als Quellen von Omega-3-Fettsäuren. Deklaration, Wirkungen und Bedeutung für die Ernährungspraxis. Ernährung im Fokus 14: 189-197
  • Richter V, Blüher M, Ceglarek U,Thiery J, Hamm M (2014): Adipositas und Omega-3-Fettsäuren: Die Rolle von Mediatoren der Entzündungsauflösung. Adipositas 8: 25-31
  • von Schacky C, Kemper M, Haslbauer R, Halle M (2014): Low  omega-3 index in 106 german elite winter endurance athletes: a pilot study. Int J Sport Nutr Exerc Metab 24: 559-564
  • Yates CM, Calder PC, Ed Rainger G (2014): Pharmacology and Therapeutics of omega-3-polyunsaturated fatty acids in chronic inflammatory disease. Pharmacol Ther 141: 272-282
  • Taha AY, Cheon Y, Faurot KF, Macintosh B, Majchrzak-Hong SF, Mann JD, Hibbeln JR, Ringel A, Ramsden CE (2014): Dietary omega–6–fatty acid lowering increases bioavailability of omega-3 polyunsaturated fatty acids in human plasma lipid pools. Prostaglandins Leucot Essent Fatty Acids 90: 151-157
  • Fischer R, Konkel A, Mehling H, Blossey K, Gapelyuk A, Wessel N, von Schacky C, Dechend R, Muller DN, Rothe M, Luft FC, Weylandt K, Schunck WH (2014): Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP –epoxygenase pathway. J Lipid Res 55: 1150-1164
  • Koletzko B, Boey CC, Campoy C, Carlson SE, Chang N, Guillermo-Tuazon MA, Joshi S, Prell C, Quak SH, Sjarif DR, Su Y, Supapannachart S, Yamashiro Y, Osendarp SJ (2014): Current information and asian perspectives on long – chain polyunsaturated fatty acids in pregnancy, lactation, and infancy: systematic review and practice recommendations from an early nutrition academy workshop. Ann Nutr Metab 65: 49-80
  • Standl M, Thiering E, Demmelmair H, Koletzko B, Heinrich J (2014): Age - dependent effects of cord blood long-chain PUFA composition on BMI during the first 10 years of life. Br J Nutr 13: 1-8
  • Kaur N, Chugh V, Gupta AK (2014): Essential fatty acids as functional components of foods – a review. J Food Sci Technol 51: 2289-2303
  • Singer P, Wirth M (2013): Zum Gehalt von Omega-3-Fettsäuren in fetten Seefischen und Fischkonserven. Deklaration als Innovation und Bedeutung für die Ernährungspraxis. Dt Lebensmittel-Rundschau 109: 643-651
  • Spite M (2013): Deciphering the role of n-3 polyunsaturated fatty acid – derived lipid mediators in health and disease. Proc Nutr Soc 2: 1-10
  • Gray B, Steyn F, Davies PSW, Vitetta L (2013): Omega-3-fatty acids: a review of the effects on adiponectin and leptin and potential implications for obesity management. European Journal of Clinical Nutrition 67: 1234-1242
  • Superko RH, Superko SM, Nasir K, Agatston A, Garrett BC (2013): Contemporary Reviews in Cardiovascular Medicine: Omega-3 fatty acid blood levels clinical significance and controversy. Circulation 128: 2154-2161
  • Ogawa S, Abe T, Nako K, Okamura M, Senda M, Sakamoto T, Ito S, and the DIMS study group (2013): Eicosapentaenoic acid improves glycemic control in elderly bedridden patients with type 2 diabetes. Tohoku J. Exp. Med. 231: 63-74
  • Koletzko B, Bauer CP, Bung P, Cremer M, Flothkötter M, Hellmers C, Kersting M, Krawinkel M, Przyrembel H, Rasenack R, Schäfer T, Vetter K, Wahn U, Weissenborn A, Wöckel A (2013): German national consensus recommendations on nutrition and lifestyle in pregnancy by the `Healthy Start – Young Family Network`. Ann Nutr Metab 63: 311-322
  • Rogers LK, Valentine CJ, Keim SA (2013): DHA supplementation: current implications in pregnancy and childhood. Pharmacol Res 70: 13-19
  • Harris WS, Pottala JV, Varvel SA, Borowski JJ, Ward JN, Mc Connell JP (2013): Erythrocyte omega-3 fatty acids increase and linoleic acid decreases with age: observations from 160,000 patients. Prostaglandins Leukot Essent Fatty Acids 88: 257-263
  • Lattka E, Koletzko B, Zeilinger S, Hibbeln JR, Klopp N, Ring SM, Steer CD (2013): Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC). Br J Nutr 109: 1196-210
  • Maskrey BH, Megson IL, Rossi AG, Whitfield D (2013): Emerging importance of omega-3 fatty acids in the innate immune response: Molecular mechanisms and lipidomic strategies for their analysis. Mol Nutr Food Res 57: 1390-1400
  • Schuchardt JP, Hahn A (2013): Bioavailability of long-chain omega-3 fatty acids. Prostaglandins Leukot Essent Fatty Acids 89: 1-8
  • Larque E, Gil-Sanchez A, Prieto-Sanchez MT, Koletzko B (2012): Omega 3 fatty acids, gestation and pregnancy outcomes. Br J Nutr 107: 77-84
  • Schmidt S, Stahl F, Mutz KO, Scheper T, Hahn A, Schuchardt JP (2012): Transcriptome-based identification of antioxidative gene expression after fish oil supplementation in normo- and dyslipidemic men. Nutr Metab 9: 45
  • Schmidt S, Stahl F, Mutz KO, Scheper T, Hahn A, Schuchardt JP (2012): Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: results from a randomized controlled trial. Lipid Health Dis 11: 105
  • Shinohara M, Mirakaj V, Serhan CN (2012): Functional metabolomics reveals novel active products in the DHA metabolome. Frontiers In Immunology 3 article 81: 1-8
  • Weylandt KH, Chiu CY, Gomolka B, Waechter SF, Wiedenmann B (2012): Omega-3 fatty acids and their lipid mediators: Towards an understanding of resolving and protektin formation. Prostaglandins Other Lipid Mediat 97: 73-82
  • Calder PC (2011): Fatty acids and inflammation: The cutting edge between food and pharma. Eur J Pharmacol 668: 50-58
  • Faber J, Berkhout M, Vos AP, Sijben JB, Calder PC, Garssen J, van Helvoort A (2011): Supplementation with a fish oil-enriched, high-protein medical food lead to rapid incorporation of PA into white blood cells and modulates immune responses within one week in healthy men and women. J Nutr 141: 964-970
  • Neubronner J, Schuchardt JP, Kressel G, Merkel M, von Schacky C, Hahn A (2011): Enhanced increase of omega-3-index in response to long-term n-3 fatty acid supplementation from triacylglycerides versus ethyl esters. Eur J Clin Nutr 65: 247-254
  • Richter V, Hamm M, Löhlein I, Bahri D, Kasper H, Klör H-U, Neuberger D, Singer P, Wahrburg U (2011): Langkettige Omega-3-Fettsäuren: Bedeutung und Versorgungskonzept. Dtsch Apoth Ztg 51: 2953-2957
  • Richter V, Hamm M (2011): Stellenwert der Omega-3-Fettsäuren in unterschiedlichen Lebensperioden. kinderkrankenschwester 30: 207-210
  • Schuchardt JP, Schneider I, Meyer H, Neubronner J, von Schacky C, Hahn A (2011): Incorporation of EPA and DHA into plasma phospholipids in response to different omega-3 fatty acid formulations – a comparative bioavailability study of fish oil vs. krill oil. Lipids Health Dis 10: 145
  • Singer P (2011). Omega-3-Fettsäuren als Therapieoption für NAFLD. MMW – Fortschr Med 153: 90-94
  • Arnold C, Konkel A, Fischer R, Schunck W-H (2010): Cytochrome P450-dependent metabolism of ω-6 and ω-3 long-chain polyunsaturated fatty acids. Pharmacol Raports 62: 536-547
  • Singer P (2010): Praktische Aspekte bei der Zufuhr von Omega-3-Fettsäuren. Ernährung und Medizin Suppl S1: 3-18
  • Bresson J-L, Flynn A, Heinonen M, Hulshof K, Korhonen H, Lagiou P, Lovik M, Marchelli R, Martin A, Moseley B, Przyrembel H, Salminen S, Strain S (JJ), Strobel S, Tetens I, van den Berg H, van Loveren H, Verhagen H (2009): Labelling reference intake values for n-3 and n-6 polyunsaturated fatty acids: Scientific opinion of the panel on dietetic products, nutrition and allergies on a request from the commission related to labelling reference intake values for n-3 and n-6 polyunsaturated fatty acids. EFSA J 1176: 1-11
  • Harris WS, Mozaffarian D, Lefevre M, Toner CD, Colombo J, Cunnane SC, Holden JM, Klurfeld DM, Morris MC, Whelan J (2009): Toward establishing dietary reference intake for eicosapentaenoic and docosahexaenoic acids. J Nutr 139: 804-819
  • Koletzko B, Lien E, Agostoni C, Böhles H, Campoy C, Cetin I, Decsi T, Dudenhausen JW, Dupont C, Forsyth S, Hoesli I, Holzgreve W, Lapillone A, Putet G, Secher NJ, Symonds M, Szajewska H, Willats P, Uauy R (2008): World Association of Perinatal Medicins Dietary Guidelines Working Group: The roles of long chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. J Perinat Med 36: 5-14
  • Hamm M, Neuberger D (2008): Omega-3 aktiv – Gesundheit aus dem Meer. Hannover: Schlütersche Verlagsgesellschaft mbH & Co KG
  • Singer P (2008): Geringer Gehalt von Omega-3-Fettsäuren bei Vegetariern und Veganern. Komplement Integr Med 49: 16-23
  • Richter V, Rassoul F, Hamm M (2007): Jugendliche oft mit Omega-3-Fettsäuren unterversorgt. Dtsch Apoth Ztg 147: 5269-5272
  • American Heart Association Nutrition Committee (2006): Scientific Statement; Diet and Lifestyle Recommendations Revision 2006. Circulation 114: 82-96
  • Deckelbaum R J, Worgall TS, Seo T (2006): n-3 Fatty acids and gene expression. Am J Clin Nutr 83 (suppl): 1520-1525
  • ISSFAL (2004): Recommendations for intake of polyunsaturated fatty acids in healthy adults.
    mehr Informationen »
  • mehr Informationen http://www.issfal.org/news-links/resources/publications/PUFAIntakeReccomdFinalReport.pdf
  • Singer P (2004): Versorgung mit Omega-3-Fettsäuren. Regulierungsmöglichkeiten, Grenzen, Perspektiven. J Orthomol Med 12: 336-349
  • Beermann C, Jelinek J, Reinecker T, Hauenschild A, Boehm G, Klör H-U (2003): Short time effects of dietary medium-chain fatty acids and n-3 long-chain polyunsaturated fatty acids on the fat metabolism of healthy volunteers. Lipids Health Dis 2: 10
  • Bahri D, Gusko M, Hamm M, Kasper H, Klör H-U, Neuberger D, Singer P (2002): Bedeutung und empfehlenswerte Höhe der Zufuhr langkettiger Omega-3-Fettsäuren. Ein Konsensus-Statement des Arbeitskreises Omega-3. Ernährungs-Umschau 49: 94-98
  • Singer P (2000): Was sind, wie wirken Omega-3-Fettsäuren? Frankfurt / Main: Umschau Zeitschriftenverlag Breitenstein GmbH
  • Simopoulos AP (1991): Omega-3 fatty acids in health and disease and in growth and development. Am J Clin Nutr 54: 438-463
  • Singer P (1991): Messung der Omega-3-Fettsäuren im Blutplasma für Bioverfügbarkeits- und Compliance-Untersuchungen. In: Schettler G (Hrsg.): Omega-3-Fettsäuren in Forschung und Praxis. Schattauer Verlag Stuttgart, New York: 1-9
  • Singer P (1986): Die Rolle der Eicosapentaensäure im Rahmen polyensäurereicher Diäten. Ernährungs-Umschau 33: 218-220

Literatur zu Omega-3-Fettsäuren und Herz-Kreislauf-Erkrankungen

  • Kleber ME., Delgado GE., Lorkowski S., März W., von Schacky C. (2016): Omega – 3 fatty acids and mortality in patients referred for coronary angiography. The Ludwigshafen risk and cardiovascular health study. Atherosclerosis 252: 175 – 181
  • Kleber  ME., Delgado GE., Lorkowski  S., März W., von Schacky  C. (2016): Data on gender and subgroup specific  analyses of omega – 3 fatty acids in the Ludwigshafen risk and cardiovascular health study. Data Brief 8: 1311 – 1321
  • Rice HB., Bernasconi  A., Maki KC., Harris WS.,von Schacky  C., Calder PC. (2016): Conducting omega – 3 clinical trials with cardiovascular outcomes:  Proceedings of a workshop held at ISSFAL  2014. Prostaglandins, Leukot  Essent  Fatty Acids 107: 30 – 42
  • Walz CP., Barry AR., Koshman SL. (2016): Omega – 3 polyunsaturated fatty acid supplementation in the prevention of cardiovascular disease. Can Pharm  J (Ott) 149:166 – 173
  • Zock  PL., Blom  WAM., Nettleton  JA., Hornstra  G. (2016): Progressing insights into the role of dietary fats in the prevention of cardiovascular disease. Curr  Cardiol  Rep18: 111 – 124
  • Bowen KJ., Harris WS., Kris – Etherton  PM. (2016):  Omega – 3 fatty acids and cardiovascular disease:  Are  there benefits? Curr  Treat Options  Cardiovasc  Med 18: 69
  • Chaudhary R., Saadin K., Bliden KP., Harris WS., Dinh B., Sharma T., Tantry US., Gurbel PA. (2016): Risk factors associated with plasma omega – 3 fatty acid levels in patients with suspected  coronary artery disease. Prostaglandins, Leukot  Essent  Fatty  Acids 113:  40 – 45
  • Singh S., Arora RR., Singh M., Khosla S. (2016):  Eicosapentaenoic  acid versus docosahexaenoic acid as options for vascular risk prevention: A fish story. Am J Ther 23: 905 – 910
  • Asztalos IB., Gleason JA., Sever S., Gedik R., Asztalos BE., Horvath KV., Dansinger ML., Lamon – Fava S., Schaefer EJ. (2016):  Effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular disease risk factors: a randomized clinical trial. Metabolism 65: 1636 – 1645
  • Harris WS. (2016): RBC omega – 3 predicts risk for death. Atherosclerosis 252: 192 – 193
  • Umemoto N., Ishii H., Kamoi D., Aoyama T., Sakakibara T., Takahashi H., Tanaka A., Yasuda Y., Suzuki S., Matsubara T., Murohara T. (2016): Reverse association of omega – 3 / omega – 6 polyunsaturated  fatty acids ratios with carotid atherosclerosis in patients on hemodialysis. Atherosclerosis  249:  65 – 69
  • Sansbury BE., Spite M. (2016):  Resolution of acute inflammation and the role of resolvins in immunity, thrombosis, and vascular biology.  Circ Res 119: 113 – 130
  • Fialkow J. (2016):  Omega – 3 fatty acid formulations in cardiovascular disease: dietary supplements are not substitutes for  prescription products. Am J Cardiovasc  Drugs 16:  229 – 239
  • Gammelmark  A., Nielsen MS., Bork CS., Lundbye – Christensen S., Tionneland  A., Overvad K., Schmidt  EB. (2016): Adipose tissue content of marine  n – 3 polyunsaturated fatty acids  ls inversely associated with myocardial infarction. J  Am Coll Cardiol  67: 1008 – 1009
  • Reiner MF., Stivala S., Limacher A., Bonetti NR., Mean M., Egloff M., Rodondi N., Aujeski D., von Schacky C., Lüscher TF., Camici GG., Beer JH. (2016): Omega – 3 fatty acids predict  recurrent venous thromboembolism or total mortality in elderly patients with acute venous thromboembolism. J Thromb Haemost  doi: 10. 1111/ jth. 13553
  • von Schacky C (2015): Omega -3 fatty acids in cardiovascular disease – an uphill battle. Prostaglandins Leucot Essent Fatty Acids 92: 41 – 47
  • Franzese CJ, Bliden KP, Gesheff MG, Pandya S, Guyer KE, Singla A, Tantry US, Toth PP, Gurbel PA (2015): Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy. Am J Cardiol 115: 1204 – 1211
  • Tani S, Takahashi A, Nagao K, Hirayama A (2015): Association of fish consumption – derived ratio of serum n-3 to n-6 polyunsaturated fatty acids and cardiovascular risk with the prevalence of coronary artery disease. 56: 260 – 268
  • Maehre HK, Jensen IJ, Elvevoll EO, Eilertsen KE (2015): ω-3 fatty acids and cardiovascular diseases: Effects, mechanisms and dietary relevance. Int J Mol Sci 16: 22631 – 22661
  • Mori TA (2014): Omega-3 fatty acids and cardiovascular disease: Epidemiology and effects on cardiometabolic risk factors. Food Funct 5: 2004 – 2019
  • Gilbert K, Bernier J, Godbout R, Rousseau G (2014): Resolvin D1, a metabolite of omega-3 polyunsaturated fatty acid, decreases post-myocardial infarct depression. Mar Drugs 12: 5396 – 5407
  • Endo J, Sano M, Isobe Y, Fukuda K, Kang JX, Arai H, Arita M (2014): 18 HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling. J Exp Med 211: 1673 – 1687
  • von Schacky C (2014): Omega-3 fatty acids in cardiovascular disease – An uphill battle. Prostaglandins Leukot Essent Fatty Acids. doi. 10.1016/j.plefa2014.05.004.
  • von Schacky C (2014): Omega-3 index and cardiovascular health. Nutr 6: 799-814
  • Merino J, Sala-Vila A, Kones R, Ferre R, Plana N, Girona J, Ibarretxe D, Heras M, Ros E, Masana L (2014): Increasing long-chain n-3 PUFA consumption improves small peripheral artery function in patients at intermediate-high cardiovascular risk. J Nutr Biochem 25: 642-646
  • Pacifico L, Giansanti S, Gallozzi A, Chiesa C (2014): Long chain omega-3 polyunsaturated fatty acids in pediatric metabolic syndrome. Mini Rev Med Chem 14: 791-804
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Omega-3-Fettsäuren und Gehirnfunktion

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  • Voggt  A., Berger  M., Obermeier  M., Löw A., Seemueller F., Riedel  M., Moeller HJ., Zimmermann  R., Kirchberg  F., von Schacky C., Severus E. (2015): Heart  rate variability and omega – 3 index in euthymic  patients with bipolar disorders. Eur Psychiatry 30: 228 - 232
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  • Cutuli D, De Bartolo P, Caporali P, Laricchiuta D, Foti F, Ronci M, Rossi C, Neri C, Spaletta G, Caltagirone C, Farioli-Vecchioli S, Petrosini L (2014): n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice. Front Aging Neurosci 6: 220
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  • Orr SK, Palumbo S, Bosetti F, Mount HT, Kang JX, Greenwood CE, Ma DWL, Serhan CN, Bazinet RP (2013): Unesterified docosahexaenoic acid is protective in neuroinflammation. J Neurochem 127: 378-393
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  • Eckert GP, Lipka U, Muller WE (2013): Omega-3 fatty acids in neurodegenerative disease: focus on mitochondria. Prostaglandins Leukot Essent Fatty Acids 88: 105-114
  • Kang JX, Gleason ED (2013): Omega-3 fatty acids and hippocampal neurogenesis in depression. CNS Neurol Disord Drug Targets 12: 460-465
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  • Loef M, Walach H (2013): The omega-6/omega-3 ratio and dementia or cognitive decline: a systematic review on human studies and biological evidence. J Nutr Gerontol Geriatr 32: 1-23
  • Luchtman DW, Song C (2013): Cognitive enhancement by omega-3 fatty acids from childhood to old age: findings from animal and clinical studies. Neuropharmacology 64: 550-565
  • Parletta N, Cooper P, Gent DN, Petkov J, O`Dea K (2013): Effects of fish oil supplementation on learning and behaviour of children from Australian indigenous remote community schools: A randomized controlled trial. Prostaglandins Leukot Essent Fatty Acids 89: 71-79
  • Pu H, Guo Y, Zhang W, Huang L, Wang G, Liou AK, Zhang J, Zhang P, Leak RK, Wang Y, Chen J, Gao Y (2013): Omega-3 polyunsaturated fatty acid supplementation improves neurologic recovery and attenuates white matter injury after experimental traumatic brain injury. J Cereb Blood Flow Metab 33: 1474-1484
  • Stonehouse W, Conion CA, Podd J, Hill SR, Minihane AM, Haskell C, Kennedy C (2013): DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial. Am J Clin Nutr 97: 1134-1143
  • Farooqui AA (2012): n-3 fatty acid-derived lipid mediators in the brain: new weapons against oxidative stress and inflammation. Curr Med Chem 19: 532-543
  • Kiecolt-Glaser JK, Belury MA, Andridge R, Malarkey WB, Hwang BS, Glaser R (2012): Omega-3 supplementation lowers inflammation in healthy middle-aged and older adults: a randomized trial. Brain Behav Immun 26: 988-995
  • Tan ZS, Harris WS, Beiser AS, Au R, Himali JJ, Debette S, Pikula A, Decarli C, Wolf PA, Vasan RS, Robins SJ, Seshadri S (2012): Red blood cell ω-3 fatty acid levels and markers of accelerated brain aging. Neurology 78: 658-664
  • Bazan NG, Molina MF, Gordon WC (2011): Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer`s, and other neurodegenerative diseases. Annu Rev Nutr 31: 321-351
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